Is this a big crisis? Should I be freaking out? They are upping my follistim by a little less than double the dose I was on before....
This is what I found on Dr. Google (at least I'm not at 75)
Abstract Purpose : To compare two GnRHa flare protocols among poor responders undergoing IVF-ET and to evaluate if a Day 6 estradiol level can predict outcome.
Methods : Retrospective analyses of GnRHa flare IVF cycles among poor responders. Group A (miniflare, N = 36) 40 g GnRHa s.c. b.i.d. from Day 3; Group B (standard flare, N = 24) 1 mg GnRHa on Days 2–3; 0.5 mg GnRHa from Day 4. ROC analysis was performed to find a Day 6 estradiol value that is predictive of cycle outcome.
Results : With the standard flare, patients required less gonadotropins and tended to have fewer cancellations and higher pregnancy rates. A Day 6 estradiol level 75 pg/mL was predictive of cycle cancellation, but not of pregnancy outcome.
Conclusions : Standard GnRHa flare offers some advantages over the miniflare. Day 6 estradiol 75 pg/mL is predictive of cycle cancellation. When the estradiol level is low on Day 6 (no flare), early cancellation should be considered.